The Chrysler New Yorker remained the company's mainstream upscale luxury model for 1960. Cosmetically, the car gained a handsome new recessed grille and a dipped front bumper, while still retaining Virgil Exner’s tall fins. The car received unibody construction for the first time in 1960, and dramatically improved rustproofing was introduced. A range of body styles were available to buyers, including two- and four-door hardtops, a convertible, and six- and nine-passenger station wagons. Rear fender trim bars continued to identify the New Yorker models. Under the hood, a unique 350-hp, 413-cid V-8 powered the car. An optional trunk lid with an integrated spare wheel cover was popular.

For 1961, a completely new front end with slanted headlights adorned the Chrysler New Yorker, and taillight placement moved to be above the bumper. The trunk lid became ribbed, and more rear fender trim bars appeared. Exner's tail fins were trimmed from the 1962 New Yorker, as with the rest of Chrysler's line. The front of the car was unchanged, with slanting headlights alongside an "open mouth" grille, but the slow-selling New Yorker two-door hardtop and convertible were canceled. Station wagons saw a different rear fender treatment that was more reminiscent of Plymouths. Horsepower dipped to 340.

The influence of Elwood Engel, Chrysler's head of design beginning in 1961, became apparent on the 1963 New Yorker, as bodies became slab-sided and square. A bold trim line ran around the car at the top of the fenders and four headlights sat level instead of being tilted. Trim bar count changed from ten to six, and placement moved from the rear to the front. The cars used the same 122-inch wheelbase as the rest of the Chrysler line. Of 27,960 New Yorkers sold, only 593 were the deluxe four-door Salon hardtop.

The cars carried forward to 1964 with only small changes to the grille and the shape of the taillights (going to square from round). A two-door hardtop rejoined the line, though only 300 were purchased. The deluxe Salon hardtop continued at the top of the New Yorker line at $5,860, which was almost $2,000 more than the four-door sedan.

The 1960 and 1961 Chrysler New Yorkers have historically been the most popular choices among collectors due to their iconic fins, but the more restrained and modern styling of the 1962-1964 models are gaining a following. Unique trim parts for the 1963 models can be harder to locate due to much lower production numbers, so the 1964 New Yorker is a slightly more practical choice, all other considerations being equal.